For localized disease (that does not metastasize to distant organs such as the lungs or bone), one of the bases of therapy is the removal of the prostate, known as a nerve-sparing radical prostatectomy. In this case, the prostate is removed by sparing the nearby nerves (which are responsible for erection and sexual function), so that impotence following conventional surgeries is less common. Since, in such cases, a part of the urethra is also removed, difficulty in holding urine, urinary incontinence often develop.

Another procedure with a similar recovery rate in terms of results is radiation therapy. Using modern equipment, a skilled radiotherapist can precisely outline the area to be irradiated, so that the radiation beam reaches almost only the area of the prostate affected by the tumour. Side effects are minimized, which are the most commonly urinary complaints (frequent, burning urination) and diarrhea due to urinary tract and rectal inflammation.

In terms of medication, almost all patients encounter hormone therapy during their illness. This is based on the fact that testosterone, which is produced mainly in the testes, but also in the prostate and adrenal glands, stimulates prostate tumour cells to divide and grow. If testosterone is deprived from the body, the growth of malignant cells is slowed down and stopped. This is the basic therapy for prostate cancer (to be honest, since testosterone is produced in the testicles, the base treatment to this day is bilateral castration). The hormone preparations are administered in the form of injections given under the skin, which must be repeated every 1 or 3 months, depending on the dose packaging. Testosterone levels are reduced by these products, so their side effects also originate from this. Decreased libido, loss of muscle mass and deterioreation of the memory are the most common. During the hormone therapy, a proper diet and regular exercise, especially weight-bearing exercises, are recommended.

There are various options to maintain and improve libido, and psychological support is also useful in these cases. To preserve cognitive functions, various activities such as chess, reading, crossword puzzles are recommended.